A pilot study of ex-vivo MRI-PDFF of donor livers for assessment of steatosis and predicting early graft dysfunction.

Sanjaya Kumar SatapathyHumberto C GonzalezJason M VanattaAndrew DyerWesley AngelSimonne S NouerMehmet KocakSatish K KediaYu JiangIan ClarkNour YadakNosratollah NezakagtooRyan HelmickPeter HortonLuis CamposUchenna AgbimBenedict MaliakkalDaniel MalufSatheesh NairHollis H HalfordJames D Eason

Published in: PloS one (2020)

In this pilot study, MRI-PDFF imaging showed potential utility in quantifying hepatic steatosis ex-vivo donor liver evaluation and the ability to predict EAD related to severe allograft steatosis in the recipient.

Keyphrases

contrast enhanced
insulin resistance
magnetic resonance imaging
high fat diet
diffusion weighted imaging
high fat diet induced
high resolution
oxidative stress
early onset
computed tomography
adipose tissue
magnetic resonance
metabolic syndrome
risk assessment
human health
skeletal muscle
clinical evaluation