Regulatory system of mGluR group II in the nucleus accumbens for methamphetamine-induced dopamine increase by the medial prefrontal cortex.

Meriem HaddarKyosuke UnoKohei HamataniShin-Ichi MuramatsuAtsumi Nitta

Published in: Neuropsychopharmacology reports (2019)

These results provided a proof that Shati/Nat8l attenuation of METH-induced DA increase is mediated by mGluR group II in the NAc. Moreover, immunohistochemical study showed a direct connection of mPFC projection neurons with NAc MSN and a connection of MSN projection neurons with a subtype of GABA interneurons in VTA.

Keyphrases

prefrontal cortex
transcription factor
high glucose
diabetic rats
spinal cord
drug induced
endothelial cells
computed tomography
image quality
metabolic syndrome
uric acid