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Integrative analysis of physiological responses to high fat feeding with diffusion tensor images and neurochemical profiles of the mouse brain.

Irene GuadillaBlanca LizarbeLaura BarriosSebastián CerdánPilar López Larrubia
Published in: International journal of obesity (2005) (2021)
The present study reveals that diet and feeding conditions elicit prominent effects on specific imaging and spectroscopic parameters of the mouse brain that can be associated to the alterations in phenotypic and endocrine variables. Together, present results disclose a neuro-inflammatory response to HFD, characterized primarily by vasogenic edema and compensatory responses in osmolyte concentrations.
Keyphrases
  • high resolution
  • physical activity
  • deep learning
  • oxidative stress
  • high fat diet
  • molecular docking
  • weight loss
  • optical coherence tomography
  • convolutional neural network
  • adipose tissue
  • insulin resistance