Fibrosis stage is an independent predictor of outcome in primary biliary cholangitis despite biochemical treatment response.
Fiorella Murillo PerezGideon M HirschfieldChristophe CorpechotAnnarosa FloreaniMarlyn J MayoAdriaan van der MeerCyriel Y PonsioenWillem J LammersAlbert ParésInvernizzi PietroMarco CarbonePier Maria BattezzatiFrederik NevensKris V KowdleyDouglas ThorburnAndrew L MasonPalak J TrivediKeith D LindorTony BrunsGeorge N DalekosNikolaos K GatselisXavier VerhelstHarry L A JanssenBettina E HansenAliya Gulamhuseinnull nullPublished in: Alimentary pharmacology & therapeutics (2019)
Assessment of fibrosis stage grants prognostic value beyond biochemical treatment response at 1 year. This highlights the need to incorporate fibrosis stage in individual risk stratification in patients with PBC, partly to identify those that may derive benefit from novel therapies.
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