Lowered quality of life in mood disorders is associated with increased neuro-oxidative stress and basal thyroid-stimulating hormone levels and use of anticonvulsant mood stabilizers.

Caroline Sampaio NunesMichael MaesChutima RoomruangwongJuliana Brum MoraesKamila Landucci BonifacioHeber Odebrecht VargasDecio Sabbatini BarbosaGeorge AndersonLuiz Gustavo Piccoli de MeloStoyanov DrozdstojEstefania MoreiraAndré F CarvalhoSandra Odebrecht Vargas Nunes

Published in: Journal of evaluation in clinical practice (2018)

These data show that lowered HRQoL in major affective disorders could at least in part result from the effects of lipid peroxidation, protein oxidation, lowered antioxidant enzyme activities, and higher levels of TSH.

Keyphrases

oxidative stress
bipolar disorder
sleep quality
dna damage
hydrogen peroxide
ischemia reperfusion injury
big data
induced apoptosis
protein protein
anti inflammatory
nitric oxide
signaling pathway
deep learning
heat stress