Login / Signup

Untargeted metabolomics yields insight into ALS disease mechanisms.

Stephen A GoutmanJonathan BossKai GuoFadhl M AlakwaaAdam PattersonSehee KimMasha Georges SavelieffJunguk HurEva L Feldman
Published in: Journal of neurology, neurosurgery, and psychiatry (2020)
In our analysis, ALS led to significant metabolic pathway alterations, which had correlations to known ALS pathomechanisms in the basic and clinical literature, and may represent important targets for future ALS therapeutics.
Keyphrases
  • amyotrophic lateral sclerosis
  • mass spectrometry
  • systematic review
  • small molecule
  • liquid chromatography
  • high resolution
  • gas chromatography mass spectrometry
  • high resolution mass spectrometry