TAC-302 promotes neurite outgrowth of isolated peripheral neurons and prevents bladder denervation related bladder dysfunctions following bladder outlet obstruction in rats.

Shohei YoshidaNaoki OrimotoHiroshi TsukiharaTakahisa NomaAtsushi HakozakiEiji Sasaki

Published in: Neurourology and urodynamics (2017)

Our data indicate that TAC-302 promotes neurite outgrowth in vitro. In addition, TAC-302 prevents BOO-induced bladder dysfunction in rats, and has a protective effect on bladder denervation.

Keyphrases

spinal cord injury
urinary tract
spinal cord
oxidative stress
mouse model
diabetic rats
electronic health record
big data
artificial intelligence