Gold(I)-Catalyzed Regioselective Cyclization to Access Cyclopropane-Fused Tetrahydrobenzochromenes.
Perla Bharath KumarChittala Emmaniel RajuPatel Hinal ChandubhaiBalasubramanian SridharGalla V KarunakarPublished in: Organic letters (2022)
Gold(I)-catalyzed efficient synthetic transformation was achieved to access the tetrahydrobenzo[ h ]cyclopropa[ c ]chromenes from allyl-substituted 1,6-diynes. Cyclopropane-fused tetrahydrobenzochromenes were obtained regioselectively in ≤92% yields. In this atom-economic organic transformation, three new C-C bonds were formed sequentially in one pot.