SARS-CoV-2 Infection (COVID-19) and Rhinologic Manifestation: Narrative Review.
Seung Hoon LeeMin Young SeoPublished in: Journal of personalized medicine (2022)
Patients with severe pneumonia of unknown etiology presented in December 2019 in Wuhan, China. A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), was isolated from the respiratory tracts of these patients. The World Health Organization (WHO) defined respiratory diseases due to SARS-CoV-2 infection as coronavirus disease 2019 (COVID-19). Many researchers have reported that the nasal cavity is an important initial route for SARS-CoV-2 infection and that the spike protein of this virus binds to angiotensin-converting enzyme 2 (ACE2) on epithelial cell surfaces. Therefore, COVID-19 is thought to significantly affect nasal symptoms and various rhinological diseases. In this review, we summarize the association between COVID-19 and various rhinological diseases, such as olfactory dysfunction, rhinosinusitis, and allergic rhinitis.
Keyphrases
- respiratory syndrome coronavirus
- coronavirus disease
- sars cov
- angiotensin converting enzyme
- angiotensin ii
- allergic rhinitis
- end stage renal disease
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- oxidative stress
- early onset
- newly diagnosed
- protein protein
- small molecule
- biofilm formation
- respiratory tract
- mechanical ventilation
- acute respiratory distress syndrome
- patient reported