Circulating Tumor DNA as a Marker of Minimal Residual Disease After Radical Resection of Colorectal Liver Metastases.
Federica MarmorinoMichele PrisciandaroMirella GiordanoElisa OrtolanStefania CrucittaFrancesco PantanoCarlotta AntoniottiMarta Maria ValentiRomano DanesiVeronica ConcaGiacomo MazzoliAlessandra BoccaccinoMartina CarulloAntonia MartinettiElisa SottotettiGianluca MasiCarlo SpositoNadia ZaffaroniMassimo MilioneGabriella FontaniniMarzia Del ReFilippo PietrantonioChiara CremoliniPublished in: JCO precision oncology (2022)
The detection of postsurgical ctDNA is an independent negative prognostic marker and identifies patients at high risk of relapse after liver metastases resection.