Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Fabian PoetzSvetlana LebedevaJohanna SchottDoris LindnerUwe OhlerGeorg StoecklinPublished in: Genome biology (2022)
While CPEB4 was previously known for its ability to stimulate cytoplasmic polyadenylation, our findings establish an additional function for CPEB4 as the RNA adaptor of a repressor complex that enhances the degradation of short-lived immediate early gene mRNAs.