Login / Signup

Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.

Fabian PoetzSvetlana LebedevaJohanna SchottDoris LindnerUwe OhlerGeorg Stoecklin
Published in: Genome biology (2022)
While CPEB4 was previously known for its ability to stimulate cytoplasmic polyadenylation, our findings establish an additional function for CPEB4 as the RNA adaptor of a repressor complex that enhances the degradation of short-lived immediate early gene mRNAs.
Keyphrases
  • gene expression
  • dna methylation
  • binding protein
  • genome wide analysis