Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity.
Hannes ManellNikolaos TsolakisChrister JansonAndrei MalinovschiKjell AlvingPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2024)
We identified several new potential plasma biomarkers specifically elevated in coincident asthma and obesity in adolescents. Four of the proteins, CCL8, IL-33, IL-17C, and CLEC7A, have previously been associated with viral mucosal host defense and Th17 cell differentiation.
Keyphrases
- insulin resistance
- metabolic syndrome
- chronic obstructive pulmonary disease
- weight loss
- sars cov
- lung function
- high fat diet induced
- type diabetes
- weight gain
- young adults
- allergic rhinitis
- physical activity
- innate immune
- liver injury
- liver fibrosis
- gene expression
- body mass index
- air pollution
- climate change
- risk assessment
- drug induced