Effect of Bedaquiline and Delamanid Pharmacokinetics on Sputum Culture Conversion and Adverse Events in Drug-Resistant Tuberculosis.

Anuj K BhatnagarAgibothu Kupparam HemanthkumarMariappan Muthu VijayalakshmiVikram VohraPadmapriyadarsini ChandrasekaranParanchi Murugesan RameshGaurav TanejaVijay Nathu ChavanBharathi JeyadeepaNamrata Kaur BhuiRajesh Solanki

Published in: Therapeutic drug monitoring (2024)

Bedaquiline and delamanid when co-administered exhibit plasma drug levels within the targeted concentrations, showing an exposure-response relationship.

Keyphrases

drug resistant
mycobacterium tuberculosis
multidrug resistant
pulmonary tuberculosis
acinetobacter baumannii
cystic fibrosis
adverse drug
cancer therapy
hiv aids
emergency department
pseudomonas aeruginosa
hepatitis c virus
antiretroviral therapy