The Perspective of Diagnostic and Prognostic Values of Lipoxygenases mRNA Expression in Colon Adenocarcinoma.
Guo-Tian RuanYi-Zhen GongLi-Chen ZhuFeng GaoXi-Wen LiaoXiang-Kun WangGuang-Zhi ZhuCun LiaoShuai WangLing YanHai-Lun XieXin ZhouJun-Qi LiuMeng-Nan ShaoJia-Liang GanPublished in: OncoTargets and therapy (2020)
In our study, we observed that the mRNA expressions of ALOX genes were associated with the diagnosis and prognosis of COAD. The results of the diagnostic analysis suggested that ALOX12 might have a diagnosis value in COAD. Besides, our comprehensive prognosis analysis indicated that ALOXE3 combined ALOX12 might serve as potential prognosis biomarkers for COAD.