Extended hypoxia-mediated H2 S production provides for long-term oxygen sensing.

Kenneth R OlsonYan GaoEric R DeLeonTroy A MarkelNatalie DruckerDavid BooneMatt WhitemanAndrea K SteigerMichael D PluthCharles R TessierRobert V Stahelin

Published in: Acta physiologica (Oxford, England) (2019)

These results show that cellular H2 S is increased during extended hypoxia and they suggest this is a continuously active O2 -sensing mechanism in a variety of cells.

Keyphrases

induced apoptosis
endothelial cells
cell cycle arrest
endoplasmic reticulum stress
cell proliferation
pi k akt