Synthesis of tetrasubstituted allenes via a 1,4-palladium migration/carbene insertion/β-H elimination sequence.
Ge ZhangXiao-Jiao FengMeng-Yao LiXiao-Ming JiGuo-Qiang LinChen-Guo FengPublished in: Organic & biomolecular chemistry (2022)
A palladium-catalyzed synthesis of tetrasubstituted allenes from aryl bromides and aryl diazoacetates is developed. This transformation proceeded via an aryl to alkenyl 1,4-palladium migration/carbene insertion/β-H elimination sequence under mild reaction conditions.
Keyphrases