LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.

Qi Wen ChenQian Qian CaiYing YangShu DongYuan Yuan LiuZhong Yi ChenChun Lan KangBing QiYi Wei DongWei WuLi Ping ZhuangYe Hua ShenZhi Qiang MengXing Zhong Wu

Published in: Clinical and translational medicine (2023)

Our results reveal an important role for BC in mediating resistance to EGFR-targeted therapy in LUAD through IMPAD1 AS and in implication for the targeted therapy resistance.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
signaling pathway
genome wide
gene expression
dna methylation