Genomic and eco-epidemiological investigations in Uruguay reveal local Chikungunya virus transmission dynamics during its expansion across the Americas in 2023.

Analía BurgueñoMarta GiovanettiVagner FonsecaNoelia MorelMauricio LimaEmerson CastroNatália R GuimarãesFelipe C M IaniVictoria BormidaMaria Noel CortinasViviana RamasLeticia CoppolaAna I BentoLeticia FrancoJairo Mendez RicoJosé LourençoLuiz Carlos Junior AlcantaraHector Chiparelli

Published in: Emerging microbes & infections (2024)

Uruguay experienced its first Chikungunya virus outbreak in 2023, resulting in a significant burden to its healthcare system. We conducted analysis based on real-time genomic surveillance (30 novel whole genomes) to offer timely insights into recent local transmission dynamics and eco-epidemiological factors behind its emergence and spread in the country.

Keyphrases

zika virus
aedes aegypti
dengue virus
copy number
public health
genome wide
single cell
gene expression
disease virus
dna methylation