Pacing induced cardiomyopathy.
Faisal M MerchantSuneet MittalPublished in: Journal of cardiovascular electrophysiology (2019)
Pacing induced cardiomyopathy (PICM) is most commonly defined as a drop in left ventricle ejection fraction (LVEF) in the setting of chronic, high burden right ventricle (RV) pacing. Recent data suggest, however, that some individuals may experience the onset of heart failure symptoms more acutely after pacemaker implantation. Definitions of PICM which emphasize drop in LVEF may underestimate the incidence of deleterious effects from RV pacing. Treatment of PICM has primarily focused on upgrade to cardiac resynchronization therapy (CRT) when LVEF has dropped. However, emerging data suggest that conduction system pacing (CSP) may offer an opportunity to prevent PICM in the first place.
Keyphrases
- cardiac resynchronization therapy
- heart failure
- left ventricular
- ejection fraction
- mycobacterium tuberculosis
- high glucose
- aortic stenosis
- mitral valve
- diabetic rats
- electronic health record
- pulmonary hypertension
- drug induced
- risk factors
- acute heart failure
- big data
- oxidative stress
- atrial fibrillation
- physical activity
- coronary artery
- endothelial cells
- congenital heart disease
- vena cava
- inferior vena cava
- combination therapy
- transcatheter aortic valve replacement