Mild Cobalt(III)-Catalyzed Allylative C-F/C-H Functionalizations at Room Temperature.
Daniel ZellValentin MüllerUttam DhawaMarkus BurschRubén Rubio PresaStefan GrimmeHarry L AndersonPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2017)
Sustainable, cobalt-catalyst enabled, synthetically significant C-F/C-H functionalizations were achieved with an ample substrate scope at an ambient temperature of 25 °C, thereby delivering perfluoroallylated heteroarenes. Detailed experimental and computational mechanistic studies on the C-F/C-H functionalizations provided strong support for a facile C-F cleavage.