Genotyping of the ABCG2 gene using Matrix-Associated Laser Desorption/Ionisation, Time-of-Flight Mass Spectrometry.

Mitsunobu TanakaI KamadaJ TakahashiT KimuraY Tani

Published in: Transfusion medicine (Oxford, England) (2017)

Jr (a-) Japanese donors had almost the homozygous for c.376 T. However, detections of more than 20 SNPs of the ABCG2 gene for the JR blood group genotyping are needed. MALDI-TOF MS-based genotyping was highly concordant with the pre-genotyped results for all ABCG2 alleles.

Keyphrases

genome wide
dna methylation
copy number
high throughput
mass spectrometry
cancer stem cells
genetic diversity
gene expression
high speed
single cell
genome wide association