Second- or third-generation tyrosine kinase inhibitors in first-line treatment of chronic myeloid leukemia in general population: Is there a real benefit?
Jim CanetPascale Cony-MakhoulSébastien OrazioEdouard CornetXavier TroussardMarc MaynadiéGabriel EtienneAlain MonnereauPublished in: Cancer medicine (2021)
In this comprehensive real-life setting, the results were consistent with clinical trials. The results are not sufficient to conclude that a NG-TKI treatment is superior with regard to these patients, despite indications regarding differences between the TKI generation effect on survival and tolerance.