A Novel Antithrombocytopenia Agent, Rhizoma cibotii , Promotes Megakaryopoiesis and Thrombopoiesis through the PI3K/AKT, MEK/ERK, and JAK2/STAT3 Signaling Pathways.

Wang ChenLinjie ZhuLong WangJing ZengMin WenXiyan XuLiLe ZouFeihong HuangQianqian HuangDalian QinQibing MeiJing YangQiaozhi WangJian-Ming Wu

Published in: International journal of molecular sciences (2022)

AECRs can promote megakaryopoiesis and thrombopoiesis through activating PI3K/AKT, MEK/ERK, and JAK2/STAT3 signaling pathways, which has the potential to treat radiation-induced thrombocytopenia in the clinic.

Keyphrases

pi k akt
signaling pathway
radiation induced
cell cycle arrest
radiation therapy
induced apoptosis
epithelial mesenchymal transition
primary care
cell proliferation
human health
risk assessment
oxidative stress
cell death