Diffusional kurtosis imaging of the corpus callosum in autism.
Yu Veronica SuiJeffrey DonaldsonLaura MilesJames S BabbFrancisco Xavier CastellanosMariana LazarPublished in: Molecular autism (2018)
Decreased DKI metrics suggested that ASD may be associated with axonal deficits such as reduced axonal caliber and density in the corpus callosum, especially in the mid and posterior callosal areas. These data suggest that impaired interhemispheric connectivity may contribute to decreased processing speed in ASD participants.
Keyphrases
- autism spectrum disorder
- intellectual disability
- spinal cord injury
- functional connectivity
- attention deficit hyperactivity disorder
- resting state
- high resolution
- traumatic brain injury
- electronic health record
- optic nerve
- big data
- white matter
- diffusion weighted imaging
- magnetic resonance
- magnetic resonance imaging
- machine learning
- computed tomography
- photodynamic therapy
- working memory