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Osteoporotic Fractures and Vertebral Body Reshaping in Children With Glucocorticoid-treated Rheumatic Disorders.

Leanne M WardJinhui MaMarie-Eve RobinsonMaya ScharkeJosephine HoKristin HoughtonAdam HuberRosie ScuccimarriJulie BarsalouJohannes RothNazih ShenoudaMary Ann MatzingerBrian LentleJacob L JaremkoKhaldoun KoujokKaren Watanabe DuffyRobert SteinAnne Marie SbrocchiCelia RoddPaivi M MiettunenClaire M A LeBlancMaggie LarcheRoman JurencakElizabeth A CummingsRobert CouchDavid A CabralStephanie AtkinsonNathalie AlosElizabeth SykesVictor N KonjiFrank RauchKerry SiminoskiBianca Lang
Published in: The Journal of clinical endocrinology and metabolism (2021)
VF occurred early and were more common than non-VF in children with GC-treated rheumatic disorders. Eighty-four percent of children with VF underwent complete vertebral body reshaping, whereas vertebral deformity persisted in the remainder of children. On average, LS BMD z scores remained low at 6 years, consistent with incomplete recovery.
Keyphrases
  • young adults
  • bone mineral density
  • rheumatoid arthritis
  • postmenopausal women
  • newly diagnosed