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Endothelium-dependent and endothelium-independent vasorelaxant effects of unripe Rubus coreanus Miq. and Dendropanax morbiferus H. Lév. extracts on rat aortic rings.

Soyi ParkKi Hoon LeeWan Seok KangJin Seok KimSunoh Kim
Published in: BMC complementary medicine and therapies (2020)
In conclusion, Hy-DP and 5-uRCK exert antihypertensive effects through different endothelium-dependent or endothelium-independent mechanisms. These findings may greatly help elucidate the mechanisms of clinical efficacy of Hy-DP:5-uRCK mixtures used for blood pressure regulation.
Keyphrases
  • nitric oxide
  • blood pressure
  • oxidative stress
  • aortic valve
  • heart rate
  • metabolic syndrome
  • skeletal muscle
  • insulin resistance
  • aortic dissection
  • blood glucose