Molecular risk classifier score and biochemical recurrence risk are associated with cribriform pattern type in Gleason 3+4=7 prostate cancer.
Nancy Y GreenlandMatthew R CooperbergAnthony C WongEmily ChanPeter R CarrollJeffry P SimkoBradley A StohrPublished in: Investigative and clinical urology (2022)
Among Gleason 3+4=7 carcinomas, large cribriform was associated with higher Decipher scores and greater BCR risk. Our results support that large cribriform is an aggressive pattern 4 subtype and should be considered a contraindication for active surveillance.