The 20-minute whole blood clotting test (20WBCT) for snakebite coagulopathy-A systematic review and meta-analysis of diagnostic test accuracy.
Thomas LambMichael AbouyannisSâmella Silva de OliveiraRachana ShenoyTulasi GeevarAnand ZachariahSanjib Kumar SharmaNavin BhattMavuto MukakaElinor HarrissDavid Griffith LallooElizabeth A AshleyWuelton Marcelo MonteiroFrank M SmithuisMichael EddlestonPublished in: PLoS neglected tropical diseases (2021)
In the absence of laboratory clotting assays, the 20WBCT remains a highly specific and fairly sensitive bedside test at detecting coagulopathy following snakebite. However, clinicians should be aware of the importance of operator training, standardized equipment and the lower sensitivity of the 20WBCT at detecting mild coagulopathy and resolution of coagulopathy following antivenom.