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D-Mannose prevents bone loss under weightlessness.

Ranli GuHao LiuMenglong HuYuan ZhuXuenan LiuFeilong WangLikun WuDanyang SongYunsong Liu
Published in: Journal of translational medicine (2023)
D-mannose protected against bone loss and UTIs in rats under weightlessness. The bone protective effects of D-mannose were mediated by inhibiting osteoclast cell fusion. Our findings provide a potential strategy to protect against bone loss and UTIs during space missions.
Keyphrases
  • bone loss
  • single cell
  • signaling pathway
  • cell therapy
  • stem cells
  • mouse model
  • mesenchymal stem cells
  • postmenopausal women
  • bone regeneration