Efficacy of Cyclooxygenase-2 Inhibitors for Headache in Acute Brain Injury: A Systematic Review.

Hector David Meza Comparan Anum Khaliq Luciola Martins Frota Daniela Pomar-Forero Bakhtawar Ahmad Erica Marnet Fernanda J P Teixeira Anita Thomas Priyank Patel Haley Brunkal Saanvi Singireddy Brandon P Lucke-Wold Carolina B Maciel Katharina M Busl

Published in: Research square (2024)

In adults with ABI, COXIBs may serve as opioid-sparing adjunctive analgesics for headache control, with limited but pointed data to indicate efficacy in the post-neurosurgical setting. However, further safety data remains to be elucidated.

Keyphrases

brain injury
subarachnoid hemorrhage
electronic health record
liver failure
chronic pain
cerebral ischemia
respiratory failure
robot assisted
drug induced
aortic dissection
machine learning
intensive care unit
nitric oxide
artificial intelligence