Diagnostic accuracy of the Panbio COVID-19 antigen rapid test device for SARS-CoV-2 detection in Kenya, 2021: A field evaluation.
Jack Karuga IrunguPeninah M MunyuaCaroline OchiengBonventure JumaPatrick AmothFrancis KuriaJohn KiiruLyndah MakayottoAhmed AbadeMarc BulterysElizabeth HunspergerGideon O EmukuleClayton OnyangoTaraz SamandariBeth A Tippett BarrVictor AkeloHerman WeyengaPatrick K MunywokiGodfrey BigogoNancy A OtienoJackton Azenga KisivuliEdwin OchiengRufus NyagaNoah C HullAmy Herman-RoloffRashid AmanPublished in: PloS one (2023)
The overall sensitivity and NPV of the Panbio™ Ag RDT were much lower than expected. The specificity of the Ag RDT was high and satisfactory; therefore, a positive result may not require confirmation by rRT-PCR. The kit may be useful as a rapid screening tool only for symptomatic patients in high-risk settings with limited access to rRT-PCR. A negative result should be interpreted based on clinical and epidemiological information and may require retesting by rRT-PCR.