Application of Organic Gel on Skin Realized by Hydrogel/Organic Gel Adhesion.

Diversity in solvent selection bestows the organic gel with appealing characteristics embracing anti-drying, anti-icing, and antifouling abilities. However, organic gel, subjected to the "toxic" inherent property of solvent, is not able to be manipulated on skin. Herein, we envisaged that introducing the hydrogel layer amid organic gel and skin to realize application of organic gel on skin. Hydrogel, inserted as the medium layer, works for the coupling role between skin and organic gel, also avoids the direct contact of organic gel towards skin. First, hydrogel system composed of acrylic acid was fabricated, meanwhile organic gel was prepared employing 2-hydroxyethyl methacrylate, ethylene glycol (EG) as solvent. Organic gel was able to adhere to hydrogel by hydrogen bonding resulting from carboxyl groups of polyacrylic acid (PAA) chains and hydroxyl groups occurring on 2-hydroxyethyl methacrylate or EG. Additionally, hydrogen bonding enabled the hydrogel to be firmly attached to skin, thus organic gel/hydrogel/skin assembly was produced. The further application of organic gel was exploited by incorporating stimuli-responsive dyes including spiropyran (SP) and rhodamine derivative (RD). This article is protected by copyright. All rights reserved.