High-dimensional analysis of the adenosine pathway in high-grade serous ovarian cancer.

Yacine BarecheSandra PommeyMayra CarneiroLaurence BuisseretIsabelle CousineauPamela ThebaultPavel ChrobakLaudine CommunalDavid AllardSimon C RobsonAnne-Marie Mes-MassonDiane ProvencherRejean LapointeJohn Stagg

Published in: Journal for immunotherapy of cancer (2021)

Our study revealed the clinical, immunological, subtype-specific impacts of eADO signaling in HGSC, unveiled the chemoprotective effect of CD39 and supports the evaluation of eADO-targeting agents in patients with ovarian cancer.

Keyphrases

high grade
low grade
single cell
cancer therapy
protein kinase