A review of mechanisms of disease across PIK3CA-related disorders with vascular manifestations.

Guillaume CanaudAdrienne M HammillDenise AdamsMiikka VikkulaKim M Keppler-Noreuil

Published in: Orphanet journal of rare diseases (2021)

Management of patients with PIK3CA-related disorders requires a multidisciplinary approach. Further results from ongoing clinical studies of agents targeting the PI3K pathway are highly anticipated.

Keyphrases

protein kinase
cancer therapy
quality improvement