Investigation of candidate genes and mechanisms underlying obesity associated type 2 diabetes mellitus using bioinformatics analysis and screening of small drug molecules.

G Prashanth Basavaraj Vastrad Anandkumar Tengli Chanabasayya Vastrad Iranna Kotturshetti

Published in: BMC endocrine disorders (2021)

The present study could deepen the understanding of the molecular mechanism of obesity associated type 2 diabetes mellitus, which could be useful in developing therapeutic targets for obesity associated type 2 diabetes mellitus.

Keyphrases

insulin resistance
weight loss
metabolic syndrome
glycemic control
type diabetes
high fat diet induced
weight gain
bioinformatics analysis
cardiovascular risk factors
skeletal muscle
drug induced
adverse drug