Efficacy of teplizumab for treatment of type 1 diabetes: A meta-analysis of randomized controlled trials.

Ehsan HeidariArman ShafieeShahab NoorianMohammad Ali RafieiMohammad AbbasiMohammad Javad AminiOmid SafariFatemeh AghamahdiMahmood Bakhtiyari

Published in: Diabetes/metabolism research and reviews (2024)

Teplizumab has a significant impact on reducing insulin dependence and enhancing endogenous insulin production in T1DM patients. However, its effect on long-term glycaemic control, as indicated by HbA1c levels, remains inconclusive.

Keyphrases

type diabetes
end stage renal disease
glycemic control
newly diagnosed
chronic kidney disease
systematic review
prognostic factors
skeletal muscle
weight loss