Cognitive Processing Speed Is Strongly Related to Driving Skills, Financial Abilities, and Other Instrumental Activities of Daily Living in Persons With Mild Cognitive Impairment and Mild Dementia.
Virginia G WadleyTyler P BullYue ZhangCheyanne BarbaR Nick BryanMichael CroweLisa DesiderioGeorg DeutschGuray ErusDavid S GeldmacherRodney GoCaroline L Lassen-GreeneOlga A MamaevaDaniel C MarsonMarianne McLaughlinIlya M NasrallahCynthia OwsleyJesse PasslerRodney T PerryGiovanna PilonietaKayla A StewardRichard E KennedyPublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)
Cognitive processing speed is strongly and consistently associated with critical daily functions in persons with MCI in models including genetic and neuroimaging biomarkers of AD risk. SPARE-AD scores also significantly correlate with IADL performance and mobility. Results highlight the central role of processing speed in everyday task performance among persons with MCI/mild dementia.