Clinically-relevant increases in serum NfL and GFAP in patients with Susac Syndrome.

Domenico PlantoneEleonora SabatelliSara LocciMariano MarrodanSini M LaaksoFarrah J MateenAmalia FeresiadouTom BuelensAssunta BiancoMarcela P FiolJorge CorrealePentti TienariPaolo CalabresiNicola De StefanoRaffaele Iorio

Published in: European journal of neurology (2023)

In SS patients, both sNFL and sGFAP levels increased compared to HC. Both biomarkers had higher levels during clinical relapse and much lower levels in remission. sNFL showed to be time sensitive to clinical changes and can be useful to monitor neuro-axonal damage in SS. This article is protected by copyright. All rights reserved.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
spinal cord injury
oxidative stress
patient reported outcomes
peritoneal dialysis
systemic lupus erythematosus
disease activity
patient reported