Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting.

Zahra SadoukiTimothy D McHughRob AarnoutseJulio Ortiz CansecoChristopher DarlowWilliam HopeJakko van IngenChristopher LongshawDavide ManisseroAndrew MeadLudovic PelligandLynette PheeJohn ReadmanMike Marvin Ruth Joseph F StandingNeil StoneEmmanuel Q WeyFrank Kloprogge

Published in: The Journal of antimicrobial chemotherapy (2021)

This review demonstrates that most publications provide insufficient data to allow for results to be evaluated, thus impairing the reproducibility of HFIM experiments. Therefore, there is a clear need for the development of laboratory standardization and improved reporting of HFIM experiments.

Keyphrases

adverse drug
staphylococcus aureus
electronic health record
emergency department
clinical practice
mass spectrometry
high resolution
deep learning
molecularly imprinted