Systemic lupus erythematosus and melioidosis.
Mohd Jazman Che RahimNurashikin MohammadMuhammad Imran KamaruddinWan Syaheedah Wan GhazaliPublished in: BMJ case reports (2019)
We reported a case of a young female patient presented with sepsis and diagnosed with melioidosis and systemic lupus erythematosus (SLE) within the same admission. She presented with 1-week history of productive cough, progressive dyspnoea together with prolonged fever, arthralgia, rashes and oral ulcers. She had septicemic shock, respiratory failure requiring intubation and ventilation in intensive care unit and subsequently developed acute renal failure requiring haemodialysis. Antibiotics and immunosuppressive treatment including low-dose intravenous cyclophosphamide were commenced. She had a remarkable recovery and was discharged after 6 weeks. There was no evidence of active SLE or relapse of melioidosis during clinic follow-ups.
Keyphrases
- systemic lupus erythematosus
- respiratory failure
- intensive care unit
- mechanical ventilation
- low dose
- high dose
- disease activity
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- multiple sclerosis
- emergency department
- primary care
- case report
- peritoneal dialysis
- acute kidney injury
- end stage renal disease
- chronic kidney disease
- rheumatoid arthritis
- clinical trial
- hepatitis b virus
- placebo controlled