Cephaloliverols A and B, two sterol-hybrid meroterpenoids from Cephalotaxus oliveri .
Chunyu JiangXiaojie FanDeli ZouZhan-Lin LiTong HanBin LinHui-Ming HuaDa-Hong LiPublished in: Organic & biomolecular chemistry (2022)
Cephaloliverols A (1) and B (2), two meroterpenoids based on a sterol and an abietane diterpene possessing a dioxane ring, were isolated from the twigs and leaves of Cephalotaxus oliveri . Their structures were established by spectroscopic analysis and quantum chemical calculation. 1 and 2 represent the first sterol-hybrid meroditerpenoids. The two compounds and their precursors decreased NO production in a dose-dependent manner in LPS-stimulated RAW 264.7 macrophages.