A variant in CYP2R1 predicts circulating vitamin D levels after supplementation with high-dose of vitamin D in healthy adolescent girls.
Sayyed Saeid KhayyatzadehMehraneh MehramizHabibollah EsmaeilySeyed Jamal MirmousaviLeila KhajaviFatemeh Nejati SalehkhaniParichehr HanachiHamidreza Bahrami-TaghanakiSaeed EslamiHasan VatanparastGordon A FernsAmir AvanMajid Ghayour-MobarhanPublished in: Journal of cellular physiology (2019)
Based on our findings, it appears that the rs10741657 variant of the CYP2R1 gene modulates the response to high-dose of vitamin D supplementation.