Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism.

Alisdair M BoagAndrea ShortLorna J KennedyHattie SymePeter A GrahamBrian Catchpole

Published in: Canine medicine and genetics (2020)

This study provides further evidence that CTLA4 promotor polymorphisms are associated with this complex genetic disease and supports an immune mediated aetiopathogenesis of canine hypoadrenocorticism.

Keyphrases

dna methylation
gene expression
genome wide
transcription factor
copy number
amino acid