Patient-determined disease steps is not interchangeable with the Expanded Disease Status Scale in mild to moderate multiple sclerosis.
Yi Chao FoongDaniel MerloMelissa GresleChao ZhuKatherine BuzzardJeannette Lechner-ScottMichael BarnettBruce TaylorTomas KalincikTrevor KilpatrickDavid DarbyPamela DobayJohan van BeekRobert HydeHelmut ButzkuevenAnneke van der WaltPublished in: European journal of neurology (2023)
The PDDS correlates better with other PROs but less with other MS-related outcome measures compared to the EDSS. There was little correlation between PDDS and EDSS longitudinally. Our findings suggest that the PDDS is not interchangeable with the EDSS.