Extracorporeal therapy of sepsis by purified granulocyte concentrates-ex vivo circulation model.

Gerd KlinkmannThomas WildBenjamin HeskampFanny DossSandra DossMagdalena MilejLea-Marie ThieleLilia GoudevaRainer BlasczykDaniel A ReuterJens AltrichterSteffen Mitzner

Published in: Artificial organs (2023)

The granulocytes demonstrated full functionality in the 6 h extracorporeal circuits after 3 days storage and in septic shock plasma. This is demonstrating the functionality of the system and encourages further clinical studies.

Keyphrases

septic shock
peripheral blood
stem cells
intensive care unit
replacement therapy