CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway.
Yujie LiYufeng ZhangHongshuo ShiXuemei LiuZifa LiJiayi ZhangXiuge WangWenbo WangXiaolin TongPublished in: Molecular medicine (Cambridge, Mass.) (2023)
This study demonstrated that CRTC2 activates the EMT process via the CREB-Smad2/3 signaling pathway in diabetic renal tubules.