Role of perilesional edema and tumor volume in the prognosis of non-small cell lung cancer (NSCLC) undergoing radiosurgery (SRS) for brain metastases.
Valerio NardoneSara NanniPierpaolo PastinaClaudia VinciguerraAlfonso CerasePierpaolo CorrealeCesare GuidaAntonio GiordanoPaolo TiniAlfonso ReginelliSalvatore CappabiancaLuigi PirtoliPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2019)
Our study, although with the limitations of a monocentric retrospective study analyzing a small cohort of patients, suggests the role of PE/GTV ratio for the development of new BMs. TV also seems to be correlated with OS, together with known clinical prognosticators. These findings, if validated in a larger prospective dataset, could help in selecting patients for the most suitable RT modality (or systemic therapy approach).