Production of parathyroid-like cells from thyroid stem cells in co-culture environment.

Özge Karabiyik AcarGülçin Delal NozhatzadehAlperen TuncerGamze Torun KöseEzgi HacihasanoğluFikrettin SahinErhan Aysan

Published in: Medicine (2022)

Using Activin A and Shh proteins, thyroid stem/progenitor cells were differentiated to parathyroid-like cells successfully in a co-culture environment. A potentially effective novel method for cell differenatiation is co-culture of cells having the same embryological origin.

Keyphrases

stem cells
induced apoptosis
cell therapy
cell cycle arrest
single cell
endoplasmic reticulum stress
oxidative stress
cell death
signaling pathway
mesenchymal stem cells
bone marrow