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Exploring the Resistance Mechanisms of Distal D835V Mutation in FLT3 to Inhibitors.

Zhiwei WangBaichun HuYu AnJian Wang
Published in: Oxidative medicine and cellular longevity (2022)
These findings indicated that the structural impact brought by D835V mutation should be considered in designing novel drugs to overcome resistance to FLT3-D835V.
Keyphrases
  • acute myeloid leukemia
  • tyrosine kinase
  • minimally invasive