1,25‑Dihydroxyvitamin D3 mitigates the adipogenesis induced by bisphenol A in 3T3-L1 and hAMSC through miR-27-3p regulation.

Donatella Paola ProvvisieroMariarosaria NegriFeliciana AmatrudoRoberta PatalanoTatiana MontòCristina de AngelisChiara GraziadioGabriella PuglieseGiulia de AlteriisAnnamaria ColaoRosario PivonelloSilvia SavastanoClaudia Pivonello

Published in: International journal of obesity (2005) (2024)

These results suggest that in cultured 3T3-L1 and hAMSC VitD induces an anti-adipogenic effect and prevents BPA pro-adipogenic effect by triggering at least in part epigenetic mechanisms involving miR-27-3p.

Keyphrases

gene expression
endothelial cells
type diabetes
metabolic syndrome
insulin resistance